Well, if you can get a signal in, and amplify it, and then get it out...... should not be a major issue (I think?) Reliability of course has been commented.
- as others have said, the connections can be important, but there are adapters (or soldering) for almost anything.
- depending on the number and type of transducers though, you might want to just check the 'per channel' output power on the amp you're considering (and, simply be aware that the advertised output is a bit of a marketing thing, so in practice can be very different between amps that are advertised with same output wattage) I think the BK Mini are 50-250W each. Its unlikely you'd feed 250W to each of them, but maybe (I think they tend to overheat when run full steam). But I think you'd need to check the amp can output high wattage to each channel (amps are often 'total' output, so as example a 400W 4 channel amp is typically better understood as 100W per channel.... but check your amp details (unless you use some special speaker wiring like putting the units in series or parallel, each BK Mini is a 'channel') The more range you have to work with, the more you can fine-tune the strength of the different effects to get a result that you are happy with. Example, I use really high output for the gear change, but all the other things like rpm, etc are much much lower output. The larger the output feasible, the more control you have to separate things like that (in SimHub).
- the other thing that can become important is an ability to set or control a 'low pass' filter. With SimHub running the show, it should not be a major issue. But, if you ever run the game audio into the BK Minis (some games don't have a telemetry feed), or use them for flight sims (I think there's some software also for that, but not sure), or even just run some music/movies/audio through them....... you should have an ability to cut off frequencies above approx 200Hz. Otherwise, signals above that start to be audible (like a bad speaker) rather than just movement of the BK. This can be done also with software in Windows (I use VoiceMeeter personally, and am constantly impressed with how powerful this software is, even if it is complex). As an example of this, I run BOTH the game audio and SimHub output for Horizon 5. Why? Because the game music and sound effects are quite cool and I like the various cut-scenes and other sound effects to come through the BKs in addition to the telemetry from SimHub.
- All this above, is one of the reasons the Behringer amps are popular. They are very powerful per channel, I think most of them can even run 2 ohm (4 ohm is usually enough, but some transducers can accept 2 ohm) and the 'D' models have a built in DSP which let's you control the low-pass filter, but even more-so give the ability to really fine tune the different frequencies inside the amp. Are they really ouputing their advertised wattage? No idea, but I'm happy with my NX1000D. They are also (normally) a fairly good price comparatively for what you get. Especially for what is needed to run ButtKickers. Is it mandatory? no. Are you still gonna have fun without all that specific control? yes, most likely. Is it a nice-to-have, in case you realize you have a very sensitive butt.... yes.
Last point, if you're looking at the small/cheap amps like Nobsound, etc, they can be quite effective (I have 2 of them), BUT, be aware that they often come with a power supply that does NOT supply enough power to drive the amp at it's advertised output. Example, my Nobsound 100x2 =200W, has a power supply of approx 19+V x 4.6A (just from memory). In theory a max output of about 90W. Which then means approx 45 W per channel. (I'm sure I've oversimplified that, and someone will correct me, but that's OK because then I will learn something too). In order to get the max 100Wx2 out of the amp, you'd need to pair it with a much more powerful power supply (separate search, and cost). This is usually written somewhere in the fine-print of the tech-specs, at least with Nobsound I've always seen it pointed out..
All of the above is also quite dependent on how/where you can mount the buttkickers. How they are mounted can make a big difference in how much power you really need, and how much dampening/isolation is needed. Too much information on that in other threads, but it is super important to the final result that you really feel, and the degree of isolation needed.
Good luck. Have fun. If you have easy/cheap access to a decent AV amp, it doesn't hurt to try. Tinkering is half the fun, as long as it doesn't hurt the wallet too much.