Hi Michael, it is different. I have the HTC Vive and investigated this topic for many weeks: The ingame Open VR setting is in conflict with the i.e. the Advanved Setting tool that some and I have installed (but don't use anymore). In Advanced Settings there is a slider for "Application supersampling" and one for "render target multiplier". "Render target multiplier" ONLY applies for the dashboard and the steam library if you want to review that through the Vive.
As soon as you launch any application with "Advanced settings" running and i.e. set to 2.0 SS, all and every application will use that setting. Now, when you launch Assetto Corsa and set the ingame OpenVR slider to i.e. 2.4 and save that, it will say that you have to restart the application. This is because it effectively changes the general setting from "Advanced settings" and writes it back to the VRsettings file in in Steam->Config.
For me this is unwanted and not very useful either in case you are playing more than one game. That is why you should not use and touch the ingame SS setting at all.
For HTC Vive and certainly for Vive Pro, Steam VR will set an overall 2.0 SS in SteamVR->settings->video even if you do not click "Manual override". You can check that by clicking "manual override" and in my case it shows 2.0 which looks like a proposal, in fact, it is the standard setting in the background.
Well, then there were a lot of comments that "Manual override" and any Application SS setting under SteamVR-Applications would multiply, i.e. 2.0 general X 2.0 for Assetto Corsa = 4.0 SS. That does not seem to be true as you can try and leave manual at 2.0 (hidden) and AC at 4.0 which would make it 8.0 SS but you will still get a race started with reduced FPS. Sure you will be in asynchronous reproduction all the time but it still does not make sense for the application to accept such a setting. It is only true, if you click "manual override" and set it to any number you like and then AC also and all my tests have left me with the impression, that SteamVR just picks the higher number from both. If you leave it unclicked, any toggled setting higher than SS 1.0 under SteamVR->Applications will be automatically preferred over the preset hidden on the SteamVR->video tab.
So what I do is, I leave ingame at 1.0 - or better - don't even touch it. I leave "manual override" for all applications untouched as well and I have set AC to 1.4 with PP filter and to 2.4 without PP.
I had posted earlier, that 3.0 SS or even higher seems to look better but on the other hand, the workload from different tracks and maximum settings AND the number of opponents varies the effective FPS output so much more than the gain from higher SS settings provides in return for just some tracks, I would have to change the SS setting all the time in order to keep 90 FPS. With 1.4 and 2.4 it is pretty stable for >90% of the tracks and 15 opponents.